The Lab Results Behind an Entrepreneur Who “Lost His Edge”
Why dopamine depletion and nutrient deficiencies, not mindset, may be the real reason you’re feeling off
He Thought He Was Burnt Out. The Truth Was Deeper.
This client came to me with a familiar story:
Low motivation
Scattered focus
Scrolling > working
Waking up tired
Quick to irritate
Relying on sugar, caffeine, or nicotine just to function
He wasn’t disengaged from his business, he loved what he did. He just couldn’t keep up. And for high-performing entrepreneurs, that disconnect is devastating.
What we discovered in his lab work confirmed what he already suspected: He wasn’t lazy. He was running on fumes.
Years of Pushing Finally Caught Up
Long hours. High stress. Constant output.
Eventually, the body can’t keep up with the demand. His system was depleted across every level: hormones, neurotransmitters, nutrients, and gut function.
Here’s what his labs revealed—and how they explained every one of his symptoms.
1. His Cortisol Curve Was Flatlined
Adrenal exhaustion is real—and measurable.
Functional hormone testing showed a severely blunted cortisol pattern:
Low on waking → grogginess and lack of motivation
Low mid-morning → poor mental stamina
Afternoon crash → brain fog, cravings, and fatigue
Flat at night → disrupted sleep and poor recovery
He wasn’t waking up restored or able to sustain focus. His energy system was tapped.
2. His Dopamine Was Tanked
Dopamine is your motivation molecule—and his was depleted.
Urine neurotransmitter testing revealed:
Low homovanillate (HVA): dopamine metabolite
Low vanilmandelate (VMA): norepinephrine/epinephrine metabolite
This explained his inability to feel drive, follow through on tasks, or get that momentum spark back.
Dopamine depletion in entrepreneurs looks like:
Mental fatigue
Difficulty focusing
Low tolerance to stress
Craving stimulation (sugar, nicotine, dopamine hits from scrolling)
3. His Brain and Body Were Nutrient Deprived
We found suboptimal levels of:
Vitamin B12
Folate
Vitamin D
These nutrients are essential for:
Neurotransmitter synthesis (dopamine, serotonin, etc.)
Methylation and nervous system repair
Emotional regulation and energy metabolism
He wasn’t producing the raw biochemical ingredients for performance.
4. His Gut Was Inflamed and Sabotaging Him
The gut-brain axis is real. In his case, it was inflamed and depleted.
Calprotectin: 534 (normal < 173) = major gut inflammation
Critically low Bacteroidetes and Firmicutes = wiped-out microbiome
Without those bacteria, he couldn’t:
Absorb nutrients
Reduce systemic inflammation
Support dopamine regulation
Recover from stress
His brain fog wasn’t a mystery. It was a microbiome problem.
The Big Takeaway: Symptoms Are Signals
Brain fog, low energy, and lack of motivation aren’t character flaws. They’re your body throwing up red flags.
When we ran his labs, we found:
Depleted neurotransmitters
Missing nutrients
Chronic inflammation
Hormone and gut dysfunction
Once we had the data, I built him a custom precision protocol to correct these issues at the root. Within weeks, his energy returned, his focus snapped back online, and his drive reignited.
When your biology is aligned, high performance becomes effortless.
Ready to See What’s Going On in Your System?
If you’ve been operating at 50% and blaming yourself— stop. Your brain isn’t broken. Your system is likely just depleted.
Schedule your free strategy call and I’ll show you:
The exact labs we use
What we look for
And how we rebuild your system from the inside out